The purpose of this work is to systematize and critically interpret Russian data on the prognostic value of inflammatory markers in patients with myocardial infarction, with a focus on predicting hospital mortality, cardiogenic shock, reperfusion disorders, left ventricular remodeling, and remote cardiovascular events. The study considers high-sensitivity C-reactive protein, interleukin-6, cellular indices of systemic inflammation based on clinical blood analysis (primarily the neutrophil-lymphocyte ratio), as well as pentraxin-3 and myeloperoxidase as a reflection of local vascular-tissue and neutrophil cascades. The review includes the results of domestic epidemiological programs and registers of acute coronary syndrome, data from multicenter cohorts, and publications from Russian research centers that studied inflammation indices in patients with acute myocardial infarction, including those with cardiogenic shock. The summary indicates that serial assessment of hs-CRP at the stabilization and discharge stage, early detection of IL-6 on the first day, and input cellular indices provide complementary risk stratification, while markers such as PTX3 and MPO expand the tissue specificity of the prognosis, which is consistent with the observations of Russian clinical centers and national registry data.