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Journal of Rare Cardiovascular Diseases
ISSN: 2299-3711 (Print)
e-ISSN: 2300-5505 (Online)
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Scandinavian Stroke Scale Outperforms NIHSS for CT-Defined Moderate–Severe Stroke at ED Entry: A Cross-Sectional Study
Dr Elizabeth C Sada
,  
Dr Prerna Veer
,  
Dr Vishruti Dobariya
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Abstract
Background: Rapid severity assessment at emergency department (ED) entry guides imaging priority and time-critical care in suspected stroke. Objective: To compare the National Institutes of Health Stroke Scale (NIHSS) and the Scandinavian Stroke Scale (SSS) for identifying clinically significant stroke at ED arrival, using non-contrast CT (NCCT) as reference. Methods: Cross-sectional study at a tertiary ED (January 2024–January 2025). Adults with suspected ischemic stroke were scored with NIHSS and SSS at presentation prior to NCCT. We summarized severity distributions, inter-scale agreement (κ), and diagnostic performance versus CT for moderate–severe involvement in the CT-classifiable subset. Results: Among 306 patients, NIHSS categorized 39.5% mild, 40.5% moderate, 19.9% severe; SSS yielded 38.2%, 40.8%, 20.9%, respectively. Agreement across three categories was moderate (κ=0.567). In the CT-classifiable subset (n=13), SSS showed higher sensitivity than NIHSS (62.5% vs 37.5%) at identical specificity (80.0% each). PPV favoured SSS (83.3% vs 75.0%) and NPV was 57.1% vs 44.4%, respectively. Conclusions: For early ED triage, SSS demonstrated higher sensitivity than NIHSS for CT-defined moderate–severe involvement while maintaining similar specificity, supporting SSS as a practical, sensitive bedside option.
Keywords
emergency department, stroke triage, Scandinavian Stroke Scale, NIHSS, diagnostic accuracy.
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Classification of Rare Cardiovascular Diseases anticoagulation atrial fibrillation atrial septal defect cardiomyopathy computed tomography congenital heart disease echocardiography electrocardiogram electrocardiography heart failure implantable cardioverter‑defibrillator magnetic resonance imaging pregnancy pulmonary arterial hypertension pulmonary hypertension rare cardiovascular disease rare disease right heart catheterization right ventricular failure
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