Rare diseases and disorders constitute important clinical prob lems. There are many concerns among physicians while planning the diagnostic and treatment process of such a heterogenous group of patients. These concerns arise not only from the rarity of cases, but also from multiple gaps in knowledge on the management of patients with rare diseases and disorders. European Parliament and the Council of the European Union [10]. Moreover, we have included rare cardio vascular disorders in this search. In addition to ICD‑10 codes [11], classes, groups, subgroups, examples