Journal of Rare Cardiovascular Diseases
ISSN: 2299-3711 (Print)
e-ISSN: 2300-5505 (Online)
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A COMPARATIVE EVALUATION OF DINOPROSTONE GEL (PGE2) FOR CERVICAL RIPENING AND INDUCTION OF LABOR AT 8 HOURS Vs 12 HOURS INTERVAL IN A TERTIARY CARE CENTRE
Dr.C.P. PADMINI
Dr. YARASAM SINDHUJA
Dr. BOBBILI CHARITHA
Dr. AMBATI UMA
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1
PROFESSOR AND HOD, DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY ,RIMS, ADILABAD
2
POST GRADUATE, DEPARTMENT OF OBSTETRICS AND GYNAECOLOGY,RIMS,ADILABAD
Received: 2025-08-15
Revised: 2025-08-14
Accepted: 2025-09-05
Published: 2025-09-22
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Abstract
AIMS: To study the difference in induction delivery interval in 8 hourly vs 12hourly intracervical dinoprostone PGE2 gel dosage intervals forinduction of labor. To study maternal & fetal outcomes in patients induced withintracervical PGE2 gel at 8 hourly vs 12 hourly dosage intervals.MATERIALS AND METHODS: This comparative study was conducted on 100 patients requiring induction oflabor after meeting the required inclusion and exclusion criteria and obtaininginformed and written consent.50 patients were induced with intracervical PGE2 gel 8-hourly called “group A” and 50 patients were induced with intracervical PGE2 gel 12-hourlycalled “group B”. RESULTS: The mode of delivery in both the groups were comparable with 64% vaginal deliveries in group A and 62% in group B. The overall mean induction deliveryinterval in group A was found to be much lower than group B. Although the rateof cesarean section was comparable in both the groups and fetal distress was themost common indication for cesarean section, the overall incidence of fetaldistress was higher in group A than group B and that of Non progress of labourwas observed more in group B. There was no statistically significant differencein maternal outcome in terms of pre-induction bishop score, mode of delivery,number of doses administered, oxytocin requirement, side effects ofprostaglandins, postpartum haemorrhage and neonatal outcome in terms ofAPGAR scores, neonatal sepsis, NICU admissions among both groups.CONCLUSION Induction of labor with intracervical dinoprostone PGE2 gel at 8 hourlyintervals has better outcomes than 12 hourly intervals in context to decreasedinduction delivery time without affecting other maternal and neonatal outcomes
Keywords
Intracervical PGE2 gel, 8 hourly and 12 hourly intervals, mode of delivery,induction delivery intervals.
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Keywords
Classification of Rare Cardiovascular Diseases
anticoagulation
atrial fibrillation
atrial septal defect
cardiomyopathy
computed tomography
congenital heart disease
echocardiography
electrocardiogram
electrocardiography
heart failure
implantable cardioverter‑defibrillator
magnetic resonance imaging
pregnancy
pulmonary arterial hypertension
pulmonary hypertension
rare cardiovascular disease
rare disease
right heart catheterization
right ventricular failure
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