Utility of the Tyg Index in Detecting IR Among Normal-Weight Individuals: A Cross-Sectional Study from South India
1
Junior Resident, Department of General Medicine, Sree Balaji MedicalCollege and Hospital, Chennai, India
2
DNB Professor of Medicine, Department of General Medicine, Sree Balaji Medical College and Hospital, Chennai, India
3
Senior Resident, Department of General Medicine,Sree Balaji Medical College and Hospital ,Chennai India
Received: 2025-07-21
Revised: 2025-08-30
Accepted: 2025-09-15
Published: 2025-09-30
TyG index are use as surrogate of the clinical and epidemiological settings for access Insulin resistance (IR). The study mainly aims to emphasise utility of TyG index as a surrogate marker for detecting IR among the normal-weight individuals. Cross-sectional research employed in this study for collection data. The study adopts a purposive sampling strategy to enrol participants aged 21 to 50 years with normal BMI. A total of 58 participants were enlisted based on sample size calculations. The finding of the study indicates that the results of the HOMA-IR test show a positive relationship with fasting glucose (r = 0.624, p < 0.0001), fasting insulin (r = not supplied but inferred extremely high), triglycerides (r = 0.347, p = 0.0076) and TyG index (r = 0.454, p = 0.0003). When it predicts IR, the TyG Index has a sensitivity of 74.36%, NPV of 56.52%, PPV of 82.86% and specificity of 68.42%.
TyG index, IR, HOMAIR, BMI, triglyceride, glucose, health.