In the first place, it should be said we all witnessed an unpresent ed event as His Holiness Pope Francis made an unexpected gesture and visited us at the Congress venue. The short description of His visit is written in the Editorial of this issue and the full texts of His speech can be found at the ESC web‑page. Probably one of the hap pies person in the whole Congress was our colleague dr Monika Komar whose daughter Rita was blessed by the Pope who held her in His hands. Please provide an abstract of 150 to 250 words. The abstract should not contain any undefined abbreviations or unspecified references.