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Journal of Rare Cardiovascular Diseases
ISSN: 2299-3711 (Print)
e-ISSN: 2300-5505 (Online)
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Distribution of Insulin Resistance Among Normal Body Weight Individuals Defined by Bmi in Patients Presenting to Tertiary Care Hospital of Chennai
Dr. Gokul K
,  
Dr. Ramachandran V
,  
Dr. Kishore Karthik S
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Abstract
Insulin resistance (IR) is a major contributor to type 2 diabetes, cardiovascular disorders, and metabolic syndrome. Although often associated with obesity, increasing evidence shows that individuals with normal body mass index (BMI) may also develop IR, especially within Asian populations where a “thin-fat” phenotype is common. This cross-sectional study was conducted at a tertiary care hospital in Chennai to evaluate the prevalence and distribution of IR among normal-BMI adults aged 18–50 years. Using the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), 67.2% of participants were found to have varying degrees of IR, despite their BMI being within the normal range. No significant associations were observed with age or gender, but fasting blood glucose showed a strong correlation with IR. The findings emphasize that BMI alone is insufficient for screening and that early detection of IR using markers such as HOMA-IR and fasting glucose may help in preventing long-term metabolic complications.
Keywords
Insulin resistance, Normal BMI, Fasting blood glucose, Metabolic syndrome, HOMA-IR.
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Classification of Rare Cardiovascular Diseases anticoagulation atrial fibrillation atrial septal defect cardiomyopathy computed tomography congenital heart disease echocardiography electrocardiogram electrocardiography heart failure implantable cardioverter‑defibrillator magnetic resonance imaging pregnancy pulmonary arterial hypertension pulmonary hypertension rare cardiovascular disease rare disease right heart catheterization right ventricular failure
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